Opportunity Information: Apply for W81XWH 19 PRARP INCASA

The DoD Peer Reviewed Alzheimer's, Innovations in Care and Support Award (FY19 PRARP InCASA) is a Department of Defense research funding opportunity aimed at backing creative, high-impact projects that improve day-to-day care and overall quality of life for people living with common symptoms associated with traumatic brain injury (TBI) and/or Alzheimer's disease and Alzheimer's disease-related dementias (AD/ADRD). Rather than focusing narrowly on basic disease mechanisms, this program is centered on practical, care-oriented innovations that can make a measurable difference for affected individuals as well as the families and care providers who support them. The program is positioned within the mission of the Peer Reviewed Alzheimer's Research Program (PRARP) and expects applicants to propose work that clearly fits that mission, while also pushing beyond standard approaches.

A key theme of the award is innovation that meaningfully challenges existing research paradigms. The program is looking for unusually creative ideas, new care models, novel support strategies, or other non-traditional approaches that improve lived outcomes. Examples of relevant research directions include interventions or tools that reduce symptoms such as cognitive problems, behavioral challenges, functional limitations, or mood-related difficulties; approaches that strengthen resiliency factors; strategies that increase or maintain independence for patients; and improved support systems, training, or resources for family members and professional care providers. Projects can address TBI, AD/ADRD, or overlapping symptom profiles and care needs, as long as the work is clearly tied to improving care and support in ways that are meaningful and testable.

The opportunity emphasizes that applications should be both innovation-based and impact-based. In practical terms, this means reviewers will expect a compelling case that the idea is truly new or distinctive, and that it has a plausible path to producing real-world benefits. The DoD also highlights that the intended benefits should extend across military, Veteran, and civilian communities, reflecting the program's interest in solutions that can translate broadly while still being responsive to the needs of service members and Veterans who may face TBI-related challenges and later-life cognitive or behavioral symptoms.

Two funding levels are offered, designed to support investigators at different career stages. Funding Level I is aimed at early-career investigators who are within three years of their first independent faculty appointment, and it is open to researchers from any field or discipline. A specific administrative requirement applies to this track: Level I applicants must include an Eligibility Statement to confirm that the named Principal Investigator meets the early-career criteria. Funding Level II is intended for more established investigators at or above the assistant professor level (or equivalent), also from any discipline. Across both tracks, the application is expected to demonstrate that the study team has appropriate experience in TBI research and/or AD/ADRD research, depending on the proposed focus, reinforcing the expectation that the team can credibly execute the work and interpret results within the relevant clinical and caregiving context.

Administratively, the opportunity is listed as discretionary funding from the Department of Defense (Department of the Army, USAMRAA) under CFDA 12.420, and it can be awarded as either a grant or a cooperative agreement. Eligibility is described as unrestricted, meaning a wide range of entity types may apply, subject to any additional eligibility clarifications in the full solicitation. The opportunity was posted May 16, 2019, with an original closing date of July 17, 2019, and it anticipated making around eight awards. The listing shows an award ceiling of 0, which commonly indicates that the maximum amount is not specified in the summary field and would need to be confirmed in the full announcement or program documentation.

  • The Department of Defense, Dept. of the Army -- USAMRAA in the science and technology and other research and development sector is offering a public funding opportunity titled "DoD Peer Reviewed Alzheimer’s, Innovations in Care and Support Award" and is now available to receive applicants.
  • Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 12.420.
  • This funding opportunity was created on May 16, 2019.
  • Applicants must submit their applications by Jul 17, 2019. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
  • The number of recipients for this funding is limited to 8 candidate(s).
  • Eligible applicants include: Unrestricted (i.e., open to any type of entity above), subject to any clarification in text field entitled Additional Information on Eligibility.
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Frequently Asked Questions (FAQs)

What is the DoD Peer Reviewed Alzheimer's, Innovations in Care and Support Award (FY19 PRARP InCASA)?

It is a Department of Defense (DoD) research funding opportunity under the Peer Reviewed Alzheimer's Research Program (PRARP) that supports creative, high-impact projects focused on improving day-to-day care and quality of life for people living with common symptoms associated with traumatic brain injury (TBI) and/or Alzheimer's disease and Alzheimer's disease-related dementias (AD/ADRD).

What is the main goal of this award?

The main goal is to fund practical, care-oriented innovations that can make a measurable difference in lived outcomes for affected individuals, as well as for the families and care providers who support them. The emphasis is on innovations in care and support rather than narrowly focusing on basic disease mechanisms.

Is this program focused on basic research about disease mechanisms?

No. The opportunity explicitly emphasizes practical innovations in care and support, not a narrow focus on basic disease mechanisms.

What kinds of projects are considered a good fit?

Projects that propose unusually creative ideas, new care models, novel support strategies, or other non-traditional approaches that improve real-world outcomes. The work should clearly fit the PRARP mission and demonstrate a credible path to meaningful benefits.

What populations or conditions can the project address?

Projects can address TBI, AD/ADRD, or overlapping symptom profiles and care needs, as long as the work is clearly tied to improving care and support in meaningful and testable ways.

What symptoms or challenges can the proposed innovations target?

Examples mentioned include approaches that reduce cognitive problems, behavioral challenges, functional limitations, or mood-related difficulties. Projects may also focus on strengthening resiliency factors, increasing or maintaining independence, or improving support systems and training/resources for family and professional care providers.

What does the program mean by "innovation"?

The program is looking for ideas that meaningfully challenge existing research paradigms. Reviewers will expect a clear rationale for why the approach is new or distinctive compared to standard approaches in the field.

What does the program mean by "impact"?

Impact refers to a plausible, well-supported path to real-world benefits. Applications are expected to show how the proposed innovation could translate into measurable improvements in care, support, and quality of life.

Who should benefit from the outcomes of the funded work?

The DoD highlights benefits that extend across military, Veteran, and civilian communities. The intent is to support solutions that can translate broadly while remaining responsive to the needs of service members and Veterans who may experience TBI-related challenges and later-life cognitive or behavioral symptoms.

How many funding levels are available under this opportunity?

Two funding levels are offered: Funding Level I and Funding Level II.

Who is Funding Level I intended for?

Funding Level I is aimed at early-career investigators who are within three years of their first independent faculty appointment. It is open to researchers from any field or discipline.

Are there any special administrative requirements for Funding Level I applicants?

Yes. Funding Level I applicants must include an Eligibility Statement confirming that the named Principal Investigator meets the early-career criteria.

Who is Funding Level II intended for?

Funding Level II is intended for more established investigators at or above the assistant professor level (or equivalent). It is also open to investigators from any discipline.

Does the study team need specific subject-matter experience?

Yes. Across both funding levels, the application is expected to demonstrate that the study team has appropriate experience in TBI research and/or AD/ADRD research, depending on the proposed focus.

What agency and program are associated with this funding opportunity?

The opportunity is offered by the Department of Defense, specifically listed under the Department of the Army, U.S. Army Medical Research Acquisition Activity (USAMRAA), within the Peer Reviewed Alzheimer's Research Program (PRARP).

What is the CFDA number for this opportunity?

The listing identifies CFDA 12.420.

What type of funding instrument might be used?

The opportunity may be awarded as either a grant or a cooperative agreement.

What does the opportunity mean by "discretionary" funding?

The listing describes it as discretionary funding from the Department of Defense, meaning it is a competitively awarded program rather than an entitlement-style award.

Who is eligible to apply?

Eligibility is described as unrestricted, meaning a wide range of entity types may apply, subject to any additional eligibility clarifications in the full solicitation.

When was the opportunity posted and what was the original deadline?

The opportunity was posted on May 16, 2019, with an original closing date of July 17, 2019.

How many awards were anticipated?

The opportunity anticipated making around eight awards.

What is the maximum award amount (award ceiling)?

The listing shows an award ceiling of 0. This commonly indicates that the maximum amount is not specified in the summary field and would need to be confirmed in the full announcement or program documentation.

Does the opportunity require that proposed work be "testable"?

Yes. The description emphasizes improving care and support in ways that are meaningful and testable, and reviewers are expected to look for a credible path to measurable benefits.

Do applicants need to stay within a single discipline?

No. Both funding levels are open to researchers from any field or discipline, as long as the proposed work fits the PRARP mission and the team has appropriate TBI and/or AD/ADRD research experience relevant to the proposal.

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